Equitable health services

Early screening could reduce prostate cancer deaths
Langa L: Health-e News, 3 November 2009

Over 4,000 men are diagnosed with prostate cancer every year in South Africa and more than half of them die, according to the Cancer Association of South Africa (CANSA). These numbers could be reduced if more men were screened. Vanitha Naidoo, head of health programmes at CANSA in KwaZulu Natal, explained that screening for prostate cancer was expensive, making it difficult for more men to access it. ‘Unfortunately there is currently no institution that offers free screenings for prostate cancer to our knowledge, which means people have to go to private care to be screened and not everyone can afford that. Most people are dependent on public hospitals and clinics for their health needs,’ she said. According to the National Cancer Registry (NCR) prostate cancer is the first of the five leading male cancers and it affects one in 23 men. ‘If screening was applied to prostate cancer as it is with other cancers such as breast and cervical cancer there would be a greater chance of diagnosing more men and offering them treatment. If a day was set aside for men to get free screening at hospitals we could see a reduction in men who die from the condition,’ said Dr Tjaart Fourie, head of Urology at the University of KwaZulu Natal.

East Africa Public Health Laboratory Networking Project for Africa
Governments of Tanzania, Kenya, Uganda and Rwanda and the World Bank: April 2010

The objective of the East Africa Public Health Laboratory Networking Project for Africa is to establish a network of efficient, high quality, accessible public health laboratories for the diagnosis and surveillance of tuberculosis and other communicable diseases. There are three components to the project, the first component being regional diagnostic and surveillance capacity. This component will provide targeted support to create and render functional the regional laboratory network. Uganda, working in close collaboration with the East, Central and Southern African Health Community (ECSA-HC), will lead the establishment of the network. The second component is joint training and capacity building. The project will support training in a range of institutions in the four countries and across the region. Tanzania will provide leadership in this area and establish a regional training hub. It will provide practical training at its state-of-the-art national health laboratory quality assurance and training centre and in-service training and post-graduate mentorships at the Muhimbili University of Health and Allied Sciences. Finally, the third component includes joint operational research, knowledge sharing and regional co-ordination, and programme management.

Eastern Cape Health dept certifies 36 "baby friendly" hospitals
Mbola B: BuaNews, 26 April 2007

The Eastern Cape Department of Health has certified 36 hospitals under the Baby Friendly Hospital Initiative (BFHI). The assessment of hospitals started in 1999 in the province when one hospital received "baby friendly" status. The BFHI is a global strategy implemented by healthcare facilities that render care to both mothers and children worldwide. It aims to increase awareness of the critical role of health services in the romotion of breastfeeding and to give guidelines for appropriate information and support to mothers. It also focuses on maternity care services which involves the holistic care of mother and baby both within the facility.

Ebola Attacked Congo Again. But Now Congo Seems to Be Winning
McNeil D: New York Times, 2 September 2018

The month-old Ebola outbreak in the Democratic Republic of Congo, which rose quickly to over 100 cases appears to be fading. More than 3,500 contacts of known cases are being followed, more than 4,000 doses of vaccine have been given and officials reported feeling hopeful enough to allow schools in the area — North Kivu Province, on the eastern border with Uganda — to open as usual. Although five experimental treatments for infected patients recently won approval for emergency use, the author reports that so far too few patients have received them to draw conclusions about how well they may work. One reason experts are reluctant to declare the outbreak contained is that some remote towns have not been visited because of armed groups in the area. Ebola experts also said they would not let down their guard because they remembered a brief, deceptive lull in the early days of the 2014 West African outbreak before it reached three capital cities and exploded, killing more than 11,000 people. Medically, the most exciting prospect on the horizon is that, as of Aug. 22, DRC has approved the emergency use of five potential treatments: two antiviral drugs, remdesivir and favipiravir; and three cocktails of antibodies originally found in recovered patients, including ZMapp, mAb114 and Regn3450-3471-3479. Previously, only about half of Ebola patients were saved if they got supportive treatment, including fluid replacement and fever control, in time. Being consistently able to cure most patients is reported to be an important advance.

Ebola’s lessons for Universal Health Coverage (UHC)
Kamal-Yanni M: Global Health Check, 11 December 2015

The 2015 UHC day comes after a year of the international community being busy in producing numerous reports on learning from the Ebola crisis. Most of the learning from these documents has focused on mechanisms for effective global response to outbreaks. However, the author argues that more attention should be directed to learning from the role of local institutions in tackling the Ebola outbreak including how critically needed advances towards UHC can be achieved. Two key ingredients for effective epidemic prevention and response require particular focus: community engagement and health systems strengthening. The WHO interim panel’s report on Ebola recognised that “Risk assessment was complicated by factors such as weak health systems, poor surveillance, little early awareness of population mobility, spread of the virus in urban areas, poor public messaging, lack of community engagement, hiding of cases, and continuing unsafe (e.g. burial) practices”.

Educating leaders in hospital management: A new model in sub-Saharan Africa
Kebede Sosena, Abebe Y, Wolde M, Bekele B, Mantopoulos J and Bradley EH: International Journal for Quality in Health Care 22(1):39-43, 2010

In this study, an initial assessment of hospital management systems demonstrated weak functioning in several management areas. In response, the authors developed a novel Master of Hospital Administration (MHA) programme, a collaborative effort of the Ethiopian Ministry of Health (MoH), the Clinton HIV/AIDS Initiative, Jimma University and Yale University. The MHA is a two-year executive style educational programme to develop a new cadre of hospital leaders, consisting of 5% classroom learning and 85% executive practice. It has been implemented with 55 hospital leaders in the position of chief executive officer within the MoH, with courses taught in collaboration by faculty of the North and the South universities. The programme has enrolled two cohorts of hospital leaders and is working in more than half of the government hospitals in Ethiopia. Lessons learned include the need to: balance education in applied technical skills with more abstract thinking and problem solving; recognise the interplay between management education and policy reform; remain flexible as policy changes have direct impact on the project; be realistic about resource constraints in low-income settings, particularly information technology limitations; and manage the transfer of knowledge for long-term sustainability. The authors hope that this programme will set a precedent for other sub-Saharan countries wishing to improve their health sector management.

Effect of human rotavirus vaccine on severe diarrhea in African infants
Madhi SA, Cunliffe NA, Steele D, Witte D, Kirsten M, Louw C, Ngwira B, Victor JC, Gillard PH, Cheuvart BB, Han HH and Neuzil KM: New England Journal of Medicine 362(4): 289–298, 28 January 2010

This study took the form of a randomised, placebo-controlled, multicenter trial in South Africa and Malawi to evaluate the efficacy of a live, oral rotavirus vaccine in preventing severe rotavirus gastroenteritis. A total of 4,939 infants were enrolled and randomly assigned to one of the three groups: 1,647 infants received two doses of the vaccine, 1,651 infants received three doses of the vaccine, and 1,641 received placebo. Of the 4,417 infants included in the per-protocol efficacy analysis, severe rotavirus gastroenteritis occurred in 4.9% of the infants in the placebo group and in 1.9% of those in the pooled vaccine group. Vaccine efficacy was lower in Malawi than in South Africa (49.4% vs. 76.9%); however, the number of episodes of severe rotavirus gastroenteritis that were prevented was greater in Malawi than in South Africa (6.7 vs. 4.2 cases prevented per 100 infants vaccinated per year). Efficacy against all-cause severe gastroenteritis was 30.2%. In conclusion, human rotavirus vaccine significantly reduced the incidence of severe rotavirus gastroenteritis among African infants during the first year of life.

Effect of incentives on insecticide-treated bed net use in sub-Saharan Africa: A cluster randomised trial in Madagascar
Krezanoski PJ, Comfort AB and Hamer DH: Malaria Journal 9(186), 27 June 2010

To date, no study has yet looked at the effect of incentives on the use of insecticide-treated nets (ITNs). This study aims to fill the research gap. It took the form of a cluster randomised controlled trial testing household-level incentives for ITN use following a free ITN distribution campaign in Madagascar. The study took place from July 2007 until February 2008. Twenty-one villages were randomised to either intervention or control clusters. At baseline, 8.5% of households owned an ITN and 6% were observed to have a net mounted over a bed in the household. At one month, there were no differences in ownership between the intervention and control groups, but net use was substantially higher in the intervention group (99% vs. 78%). After six months, net ownership had decreased in the intervention compared to the control group (96.7% vs. 99.7%). There was no difference between the groups in terms of ITN use at six months; however, intervention households were more likely to use a net that they owned (96% vs. 90%). The study concludes that providing incentives for behaviour change is a promising tool that can complement traditional ITN distribution programmes and improve the effectiveness of ITN programmes in protecting vulnerable populations, especially in the short-term.

Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): A randomised trial
Lester RT, Ritvo P, Mills EJ, Kariri A, Karanja S, Chung MH et al: The Lancet 376(9755):1838-1845, 27 November 2010

This study aimed to assess whether mobile phone communication between health-care workers and patients starting antiretroviral therapy (ART) in Kenya improved drug adherence and suppression of plasma HIV-1 RNA load. Between May 2007 and October 2008, a total of 538 randomly assigned HIV-infected adults who initiated ART in three clinics in Kenya were selected. Patients in the intervention group received weekly SMS messages from a clinic nurse and were required to respond within 48 hours. Adherence to ART was reported in 168 of 273 patients receiving the SMS intervention compared with 132 of 265 in the control group. Suppressed viral loads were reported in 156 of 273 patients in the SMS group and 128 of 265 in the control group. The number needed to treat (NNT) to achieve greater than 95% adherence was nine and the NNT to achieve viral load suppression was 11. The study concludes that patients who received SMS support had significantly improved ART adherence and rates of viral suppression compared with the control individuals. Mobile phones might be effective tools to improve patient outcomes in resource-limited settings.

Effects of Response to 2014–2015 Ebola Outbreak on Deaths from Malaria, HIV/AIDS, and Tuberculosis, West Africa
Parpia A; Ndeffo-Mbah M; Wenzel N; Galvani A: Emerging infectious diseases 22(3) 433-41, 2016

Response to the 2014–2015 Ebola outbreak in West Africa overwhelmed the healthcare systems of Guinea, Liberia, and Sierra Leone, reducing access to health services for diagnosis and treatment for the major diseases that are endemic to the region: malaria, HIV/AIDS, and tuberculosis. To estimate the repercussions of the Ebola outbreak on the populations at risk for these diseases, the authors developed computational models for disease transmission and infection progression. They estimated that a 50% reduction in access to healthcare services during the Ebola outbreak exacerbated malaria, HIV/AIDS, and tuberculosis mortality rates by additional death counts of 6,269 (2,564–12,407) in Guinea; 1,535 (522–2,8780) in Liberia; and 2,819 (844–4,844) in Sierra Leone. The authors report that the 2014–2015 Ebola outbreak was catastrophic in these countries, and its indirect impact of increasing the mortality rates of other diseases was also substantial.

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